Welcome to the Department of Physiology and Biophysics!
Welcome to the Department of Physiology and Biophysics! We are over 170 faculty, fellows, students, and staff. Building on strong traditions, we strive to be a world leader in our parallel missions of research, teaching, and service. Our founding chair John Macleod was a future Nobel Laureate, Corneille Heymans was another laureate trained in the Department, and a Lasker Award winner Carl J. Wiggers chaired the Department for a generation. Our research mission benefits from a rare combination of faculty who address important translational problems in physiology and biophysics across a broad spectrum of integration—from the level of the atomic structure of molecules, through living cells and organ systems, and up to the whole organism. The major programmatic foci of our research are cardiovascular, renal, and neuronal function in health and disease. Our educational mission includes a strong PhD-training program as well as a new Master’s program in medical physiology that has attracted considerable interest. Our service mission has a strong impact at the local, national, and international levels.
Mission: research, education, service
Research Interest: integration of physiology and biophysics from atom to whole organism
Former President of FASEB, Secretary General of the IUPS, Co-director of Case’s MSTP
Co-home to textbook Medical Physiology
Post-Bacc Application Deadline
June 15, 2016
June 15th, 2016 at midnight is the official deadline for submitting applications for the MS in Medical Physiology Program (Post-Bacc Program). Any online applications that have been initiated at that time will be considered even if it takes the applicant a week or so to complete the application (ex. provide your official transcript, provide GRE, MCAT, or DAT scores, provide your personal statement, provide 3 letters of recommendation). The admissions committee will review your application once it is complete and all application materials are received. If you have any questions, please contact Dr. Nosek (Thomas.Nosek@Case.edu, 216-368-3242). Contact us if you need assistance.
4th Annual Ulrich Hopfer Lecture
March 17, 2016
The Department of Physiology and Biophysics will host Dr. Ernest Wright, FRS, of the UCLA School of Medicine, who will present the fourth annual Ulrich Hopfer lecture on Thursday, March 17, 2016 at 4:00 p.m in SOM E-501.
The title of Dr. Wright's lecture is “Basic Physiology to Translational Medicine: Lessons from SGLTS.“
The Department hosts the Hopfer lecture each Spring in honor of Professor Emeritus Ulrich Hopfer, M.D., Ph.D. (photo at left)
Open House for Post-Bacc Medical Physiology Program
April 9, 2016
The Department has scheduled an Open House for April 9th, 2016. Prospective students can hear all about our educational programs, tour the CWRU campus and department laboratories, and meet faculty and students. Please click here for more info.
Congratulations to Dr. Chris Ford & Dr. Nick Courtney...
Jan. 7, 2016
on acceptance of the paper "Mechanisms of 5HT1A receptor mediated transmission in dorsal raphe serotonin neurons."
Courtney NA & Ford CP (2016), Journal of Physiology. In press.
Congratulations to Dr. Mausita Karmakar & Dr. Michael Katsnelson...
Dec. 28, 2015
on acceptance of the paper "Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP."
Karmakar M., Katsnelson, M., Dubyak G.R., Pearlman, E., Nature / Communications. In press.
Congratulations to Dr. Michelle Jennings Nassal!
Nov. 20, 2015
Michelle Jennings Nassal publicy defended her doctoral dissertation on Friday, November 20 at 2:00 p.m. in SOM Robbins E-501.
The title of Dr. Jennings Nassal's dissertation is "Identifying Novel Therapeutic Targets for Reentrant Amhythimias."
A reception followed the defense at 3:00 p.m. in the Department of Physiology and Biophysics fifth floor bridge area.
Congratulations to Dr. Matt Cohen!
Nov. 6, 2015
Matt Cohen, a doctoral candidate in the lab of Dr. Vera Moiseenkova-Bell, publicy defended his dissertation on Friday, November 6 at 3:30 p.m. in SOM Robbins E-501.
The title of Matt's dissertation is "Regulation of endogenous TRV2 ion channel by growth factors in neuronal cells".
A reception followed the defense at 4:30 p.m. in the Department of Physiology and Biophysics fifth floor bridge area.
Congratulations to Dr. Nick Courtney!
Oct. 30, 2015
Nick Courtney, a Ph.D. candidate in the lab of Dr. Chris Ford, publicly defended his doctoral dissertation on Friday, October 30, 2015 at 3:00 p.m. in SOM Robbins E-504.
The title of Nick's dissertation is “Mechanisms of autoreceptor-mediated inhibition in central monoamine neurons.”
A reception followed the defense at 4:00 p.m. in the Department of Physiology and Biophysics fifth floor bridge area.
1st Annual Matthew Levy Lecture
Oct. 12, 2015
The Department hosted the First Annual Matthew Levy Lecture at 3:00 p.m. on Monday, October 12, 2015 in SOM Robbins E-501.
The guest lecturer was Dr. Peter Libby, the Mallinckrodt Professor of Medicine and a cardiovascular specialist at Harvard Medical School and Brigham and Women's Hospital.
The title of Dr. Libby's lecture was “Inflammation in Atherosclerosis –a Translational Journey”.
A pre-lecture reception was held at 2:30 p.m. in the Department's lobby.
Congratulations to Dr. Walter Boron
Sept. 28, 2015
Dr. Walter Boron, the Myers/Scarpa Professor and Chair of the Department of Physiology and Biophysics, received a DURIP award from the Office of Naval Research for equipment for gas channel research, effective August 15, 2015.
Sept. 25, 2015
The annual Recknagel Symposium was held, as a part of the Department Annual Retreat at the Kalihari Resort, on Friday afternoon, September 25, from 2:30 - 4:00 p.m. Six of our second year doctoral students presented on projects from their first year laboratory rotations.
Winners of the 2015 Recknagel Symposium awards are:
Yvonne Gicheru, Ph.D. candidate - Best research presentation for "Pentameric Ligand-Gated Ion Channels Analyzed By Nanodisc Technology". Yvonne is in the lab of Dr. Sudha Chakrapani.
Di Hu, Ph.D. candidate - Best academic record (2014-2015). Di is in the lab of Dr. Xin Qi.
During the first year of doctoral training, students in the Department rotate in three different laboratories. The goal of these rotations is to identify a subject area of interest, and a mentor for future research. After completion of the research rotations, each student presents one of the projects to the entire department in a formal setting known as The Richard Recknagel Symposium. Professor Richard Recknagel was Chairman of Physiology from 1976 to 1986. He was an admired thinker and investigator who took a keen interest in mentoring young students and faculty. In his memory, the Department established this Symposium.
2015 DPB Annual Retreat and Recknagel Symposium
Sept. 24, 2015
Sept. 25, 2015
The Department of Physiology and Biophysics held its annual retreat at the Kalahari Resort in Sandusky, OH on Thursday and Friday, September 24 and 25, 2015.
The annual Recknagel Symposium also took place, as part of the retreat, on Friday afternoon, September 25. Six of our second year doctoral students presented on projects from their first year laboratory rotations.
Congratulations to Dr. Rossana Occhipinti
Sept. 18, 2015
Congratulations to Rossana Occhipinti, Ph.D. on the award of a K01 grant from the National Institute of Diabetes and Digestive and Kidney Diseases for the project:
"Acid secretion and intracellular pH regulation in proximal-tubule cells"
The award was effective on September 18, 2015 and the project will run through August 31, 2020.